AG-490
2-Cyano-3-[3,4-dihydroxyphenyl]-N-[phenylmethyl]-2-propenamide; Tyrphostin AG 490
A potent and specific inhibitor of the JAK-2 tyrosine kinese. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced papooses. AG-490 does not significan
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Chemical Formula |
C17H14N2O3 |
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Molecular Weight |
F.W. 294.30 |
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CAS # |
134036-52-5 |
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Safety Information |
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Health Hazard |
2 |
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Fire Hazard |
1 |
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Reactivity |
0 |
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Test |
Specification |
| Appearance | Pale yellow-green crystal |
| Melting Point | 213°C |
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Storage Information |
DEEP FREEZE: Keep tightly closed. |
Chemical information and descriptions have been provided by Spectrum Chemicals.
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